FANCB Antibody - CD BioSciences

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FANCB Antibody

FANCB Antibody

SPA-03792

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0.025 mL Online Inquiry
0.1 mL Online Inquiry
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Target Information
Target Name FANCB
Gene Abbr. FANCB
Gene ID 2187
Full Name FA complementation group B
Alias FA2, FAAP90, FAAP95, FAB, FACB
Introduction The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq]
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 2B10
Isotype IgG2A Kappa
Immunogen FANCB (NP_689846.1, 750 a.a. ~ 858 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GSENFLIDNMAFTLEKELVTLSSLSSAIAKHESNFMQRCEVSKGKSSVVAAALSDRRENIHPYRKELQREKKKMLQTNLKVSGALYREITLKVAEVQLKSDFAAQKLSN.
Usage
Application WB, ELISA
Dilutions Western Blot (1:500)
Reactivity Human
Specificity FANCB - Fanconi anemia, complementation group B.
Storage & Handling
Storage Buffer In 1X PBS, pH 7.4.
Preservative No Preservative
Storage Temp. Aliquot and store at -20 °C or -80 °C.
Handling Avoid freeze-thaw cycles.

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