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ERp72 Antibody
SPA-03692
Size | Price |
25 µg | Online Inquiry |
100 µg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | ERp72 |
Gene Abbr. | PDIA4 |
Gene ID | 9601 |
Full Name | protein disulfide isomerase family A member 4 |
Alias | ERP70, ERP72, ERp-72 |
Introduction | Secretory proteins translocate into the endoplasmic reticulum (ER) during synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds. This process is called oxidative protein folding. Protein disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds. Other ER resident proteins that possess thioredoxin homology domains, including ER stress protein 72 (ERp72), constitute the PDI family. ERp72 contains three thioredoxin homology domains (3) and plays a role in the formation and isomerization of disulfide bonds. |
Product Details | |
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Host | Rabbit |
Clonality | Polyclonal |
Clone No. | N/A |
Immunogen | Synthetic peptide corresponding to the sequence of human ERp72. |
Source/Purification | Antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human ERp72. Antibodies are purified by peptide affinity chromatography. |
Usage | |
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Application | WB |
Dilutions | Western Blot (1:1000) |
MW(KDa) | 72 |
Reactivity | Human, Mouse, Rat, Monkey |
Sensitivity | Endogenous |
Specificity | Detects endogenous levels of total ERp72 protein. |
Storage & Handling | |
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Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA and 50% glycerol. |
Storage Temp. | Store at -20 °C. |
Handling | Do not aliquot the antibody. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.