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ERp57 Antibody
SPA-03691
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | ERp57 |
| Gene Abbr. | PDIA3 |
| Gene ID | 2923 |
| Full Name | protein disulfide isomerase family A member 3 |
| Alias | ER60, ERp57, ERp60, ERp61, GRP57 |
| Introduction | Secretory proteins translocate into the endoplasmic reticulum (ER) after their synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds. This process is called oxidative protein folding. Disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds. Other ER resident proteins that possess the thioredoxin homology domains, including endoplasmic reticulum stress protein 57 (ERp57), constitute the PDI family. ERp57 interacts with calnexin and calreticulin and is suggested to play a role in the isomerization of disulfide bonds on certain glycoproteins. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ERp57. |
| Usage | |
|---|---|
| Application | WB, IF, IHC |
| Dilutions | Western Blot (1:500-1:3000); Immunofluorescence (1:100-1:1000); Immunohistochemistry (10-1:500) |
| MW(KDa) | 57 |
| Reactivity | Human, Mouse, Rat |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.1 M Tris (pH 7), 0.1 M Glycine, 20% Glycerol. |
| Preservative | 0.01% Thimerosal |
| Storage Temp. | Aliquot and store at -20 °C or -80 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.