EphB2 Antibody - CD BioSciences

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EphB2 Antibody

EphB2 Antibody

SPA-03555

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Target Information
Target Name EphB2
Gene Abbr. EPHB2
Gene ID 2048
Full Name EPH receptor B2
Alias BDPLT22, CAPB, DRT, EK5, EPHT3
Introduction Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse EphB2. Val27-Lys548. Accession # P54763.
Usage
Application WB, FC, IHC, IF
Dilutions Western Blot (0.1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells); Immunohistochemistry (1-15 µg/mL); Immunofluorescence (5-15 µg/mL)
Reactivity Human, Mouse
Specificity Detects mouse and human EphB2 in direct ELISAs and Western Blots. In Western Blots, approximately 5% cross-reactivity with recombinant rat (rr) EphB1, recombinant mouse (rm) EphA8, rmEphA6, rmEphB6, rmEphA3, rmEphA4, rmEphA7, rrEphA5, recombinant human EphA1, rmEphA2 and rmEphB3 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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