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EPAC1 Antibody
SPA-03427
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | EPAC1 |
| Gene Abbr. | RAPGEF3 |
| Gene ID | 10411 |
| Full Name | Rap guanine nucleotide exchange factor 3 |
| Alias | CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910 |
| Introduction | EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signaling in part through protein kinase A (PKA). EPAC signaling plays a significant role in a number of cellular processes including migration and focal adhesion formation exocytosis insulin signaling axon growth and guidance and neurotransmitter release. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 5D3 |
| Immunogen | Recombinant fragment of human Epac1. |
| Source/Purification | Antibody is produced by immunizing animals with a recombinant fragment of human Epac1. |
| Usage | |
|---|---|
| Application | WB |
| Dilutions | Western Blot (1:1000) |
| MW(KDa) | 100 |
| Reactivity | Human, Mouse, Rat |
| Sensitivity | Endogenous |
| Specificity | It detects endogenous levels of total Epac1 protein. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. |
| Preservative | Less than 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Do not aliquot the antibody. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.