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Entrectinib (RXDX-101)
SPC-00800
CAS No. 1108743-60-7
| Size | Price |
| 5 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Trk receptor inhibitor ; ALK inhibitor ; ROS1 inhibitor ; Autophagy activator
| Description |
|---|
| Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1108743-60-7 |
| Description | Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2. |
| Formula | C31H34F2N6O2 |
| Molecular Weight | 560.64 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NMS-E628 |
| SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)C(=O)NC3=NNC4=C3C=C(C=C4)CC5=CC(=CC(=C5)F)F)NC6CCOCC6 |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.