Online Inquiry
Entinostat (MS-275)
SPC-00799
CAS No. 209783-80-2
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 50 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
HDAC inhibitor ; Autophagy activator ; Apoptosis related activator
| Description |
|---|
| Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 209783-80-2 |
| Description | Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3. |
| Formula | C21H20N4O3 |
| Molecular Weight | 376.41 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | SNDX-275 |
| SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3 |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.