ENMD-2076 L-(+)-Tartaric acid - CD BioSciences

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ENMD-2076 L-(+)-Tartaric acid

ENMD-2076 L-(+)-Tartaric acid

SPC-00796

ENMD-2076 L-(+)-Tartaric acid

CAS No. 1291074-87-7

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FLT3 inhibitor ; Aurora Kinase inhibitor ; VEGFR inhibitor

Description
ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.
Product Details
CAS No. CAS No. 1291074-87-7
Description ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.
Formula C25H31N7O6
Molecular Weight 525.56
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1=CC(=NN1)NC2=CC(=NC(=N2)C=CC3=CC=CC=C3)N4CCN(CC4)C.C(C(C(=O)O)O)(C(=O)O)O
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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