Encorafenib (LGX818) - CD BioSciences

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Encorafenib (LGX818)

Encorafenib (LGX818)

SPC-00793

Encorafenib (LGX818)

CAS No. 1269440-17-6

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Raf inhibitor

Description
Encorafenib (LGX818) is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.
Product Details
CAS No. CAS No. 1269440-17-6
Description Encorafenib (LGX818) is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.
Formula C22 H27 Cl F N7 O4 S
Molecular Weight 540.01
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C)N1C=C(C(=N1)C2=C(C(=CC(=C2)Cl)NS(=O)(=O)C)F)C3=NC(=NC=C3)NCC(C)NC(=O)OC
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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