EMR3 Antibody - CD BioSciences

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EMR3 Antibody

EMR3 Antibody

SPA-03395

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Target Information
Target Name EMR3
Gene Abbr. ADGRE3
Gene ID 84658
Full Name adhesion G protein-coupled receptor E3
Alias EMR3
Introduction EMR3 is an Orphan-B GPCR with an unknown ligand. Two variants are produced by alternative splicing. One form encodes a 652-amino acid GPCR consisting of two EGF-like domains and a mucin stalk, while the other is a truncated soluble form containing only two EGF-like domains. EMR3 and EMR2 share a high degree of sequence identity in the transmembrane domains. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 908235
Isotype IgG2B
Immunogen NS0 mouse myeloma cell line transfected with human EMR3. Met1-Tyr652. Accession # Q9BY15.
Usage
Application FC
Dilutions Flow Cytometry (0.25 μg/10^6 cells)
Reactivity Human
Specificity Detects human EMR3 in direct ELISAs.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.