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EBI2/GPR183 Antibody
SPA-04721
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | GPR183 |
| Gene Abbr. | GPR183 |
| Gene ID | 1880 |
| Full Name | G protein-coupled receptor 183 |
| Alias | EBI2, hEBI2 |
| Introduction | G-protein coupled receptor 183 (EBI2) belongs to the G-protein coupled receptor 1 family of proteins. It is an orphan seven-transmembrane receptor originally identified as most up-regulated gene (>200-fold) in EBV-infected cells. It plays a central role during humoral immunity. It promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses. It is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also reported to be highly expressed in lung, heart and gastrointestinal tract. EBI2 deficiency in mice led to a reduction in the early antibody response to a T-dependent antigen. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | A portion of amino acids 300-350 of human EBI2 was used as the immunogen. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (2-4 µg/mL) |
| Reactivity | Human, Primate |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.2 mL PBS and 0.05% BSA. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.