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Doxorubicin (Adriamycin) HCl
SPC-00752
CAS No. 25316-40-9
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Antineoplastic and Immunosuppressive Antibiotics inhibitor; Topoisomerase inhibitor; ADC Cytotoxin ; Mitophagy activator; AMPK inhibitor; Apoptosis related activator; Anti-infection chemical
| Description |
|---|
| Doxorubicin (Adriamycin, NSC 123127, DOX) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 25316-40-9 |
| Description | Doxorubicin (Adriamycin, NSC 123127, DOX) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation. |
| Formula | C27H29NO11.HCl |
| Molecular Weight | 579.98 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC 123127, DOX |
| SMILES | CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O.Cl |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.