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Dovitinib (TKI258) Lactate
SPC-00747
CAS No. 915769-50-5 (monohydrate)
| Size | Price |
| 10 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
FLT3 inhibitor ; c-Kit inhibitor ; FGFR inhibitor ; PDGFR inhibitor ; VEGFR inhibitor
| Description |
|---|
| Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 915769-50-5 (monohydrate) |
| Description | Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. |
| Formula | C24H29FN6O5 |
| Molecular Weight | 500.52 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | CHIR258 |
| SMILES | CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N.O |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.