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DMXAA (Vadimezan)
SPC-00733
CAS No. 117570-53-3
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
VDA chemical ; STING agonist ; TNF-alpha modulator ; Anti-infection inhibitor
| Description |
|---|
| DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 117570-53-3 |
| Description | DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3. |
| Formula | C17H14O4 |
| Molecular Weight | 282.29 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC 640488, ASA-404 |
| SMILES | CC1=C(C2=C(C=C1)C(=O)C3=CC=CC(=C3O2)CC(=O)O)C |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.