TIPS-5-Ethynyl-dU-CEP

Synonyms (s): TIPS-5-EdU CEP, TIPS-5-Ethynyl dU CEP, TIPS-5-Ethynyl dU phosphoramidite

Empirical Formula (Hill Notation): C₅₀H₆₇N₄O₈PSi

Size: 100 mg

Product Introduction

Molecular Weight	911.15
Form	Powder
Reaction Suitability	Reaction type: click chemistry
Storage Temp.	-20 °C

Application

This functional phosphoramidite is used to introduce click handles universally (5′ internal and 3′ end) into oligonucleotides under standard conditions for solid phase synthesis. Afterwards the oligonucleotide (RNA, PNA, DNA) can be efficiently conjugated using a copper catalyzed click reaction to azide functionalized moieties such as fluorescent dye azides and azido amino acids. In contrast to 5-Ethynyl dU CEP, TIPS-5-EdU CEP allows side product free synthesis of highly modified oligonucleotides (>10 modifications).

Safety Information

Storage Class Code	11 - Combustible Solids
WGK	WGK 3

For research use only. Not for clinical use.