Cat#: CLP-0096
tert-Butyl 12-amino-4,7,10-trioxadodecanoate
Synonyms (s): Amino-PEG3-tert-butyl ester, tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate
Empirical Formula (Hill Notation): C13H27NO5
Size: 1 g; 5 g
Product Introduction
| Molecular Weight | 277.36 |
| NACRES | NA.22 |
| CAS Number | 252881-74-6 |
| MDL Number | MFCD06201017 |
| PubChem Substance ID | 57652942 |
| Assay | ≥80% |
| Form | Solid |
| Reaction Suitability | Reagent type: Cross-linking reagent |
| Smiles String | CC(C)(C)OC(=O)CCOCCOCCOCCN |
| InChI | 1S/C13H27NO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11,14H2,1-3H3 |
| InChI key | CWFSAZJIJBTKRC-UHFFFAOYSA-N |
| Storage Temp. | -20 °C |
Application
tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.Synthesis of polycationic adamantane-based dendrons for cell imaging.Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).
Safety Information
| Signal Word | Warning |
| Target Organs | Respiratory system |
| Hazard Classifications | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Storage Class Code | 11 - Combustible Solids |
| WGK | WGK 3 |
| Flash Point(F) | 337.5 °F |
| Flash Point(C) | 169.7 °C |
For research use only. Not for clinical use.
