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Photo-reactive Clickable cis-Sterol Probe

Cat#: CCR-0238

Photo-reactive Clickable cis-Sterol Probe

Empirical Formula (Hill Notation): C30H46N2O3

Size: 5 mg

Product Introduction

Molecular Weight 482.70
Assay 95%
Form Semisolid
Reaction Suitability Reaction type: click chemistry
Smiles String C[C@H](CCC(=O)OCCCCC#C)[C@H]1CCC2C3CC4(N=N4)[C@@H]5C[C@H](O)CC[C@]5(C)C3CC[C@]12C
InChI 1S/C30H46N2O3/c1-5-6-7-8-17-35-27(34)12-9-20(2)23-10-11-24-22-19-30(31-32-30)26-18-21(33)13-15-29(26,4)25(22)14-16-28(23,24)3/h1,20-26,33H,6-19H2,2-4H3/t20-,21-,22?,23-,24?,25?,26-,28-,29-/m1/s1
InChI key ZJMZIZZWLLQHJO-HFMSFSOYSA-N
Storage Temp. -20 °C

Application

Photo-activatable sterol probe for the bioorthogonal tagging and enrichment of sterol-binding biomolecules. This sterol probe contains an intact steroid core structure bearing a diazirine UV-activatable cross-linking group, as well as an alkyne group for click-chemistry mediated adduction of reporter and affinity tags. The probes are cell-permeable, allowing for in situ labeling of biomolecules in live cells, as well as in cell extracts in vitro.

Safety Information

Storage Class Code 13 - Non Combustible Solids
WGK WGK 3

For research use only. Not for clinical use.