Cat#: CCR-0087
NVOC2-Q-rhodamine-5-PEG3-azide
Synonyms (s): ortho-Nitroveratryloxycarbonyl-Q-rhodamine-5-PEG3-azide
Empirical Formula (Hill Notation): C55H56N8O19
Size: 1 mg; 5 mg
Product Introduction
| Molecular Weight | 1133.08 |
| NACRES | NA.22 |
| CAS Number | 1352809-21-2 |
| MDL Number | MFCD24849720 |
| PubChem Substance ID | 329767394 |
| Assay | 95% |
| Form | Solid |
| Reaction Suitability | Reaction type: click chemistry |
| Smiles String | COc1cc(COC(=O)N2CCCc3cc4c(Oc5cc6N(CCCc6cc5C47OC(=O)c8cc(ccc78)C(=O)NCCOCCOCCOCCN=[N+]=[N-])C(=O)OCc9cc(OC)c(OC)cc9[N+]([O-])=O)cc23)c(cc1OC)[N+]([O-])=O |
| InChI | 1S/C55H56N8O19/c1-72-47-24-35(43(62(68)69)28-49(47)74-3)30-79-53(66)60-13-5-7-32-22-39-45(26-41(32)60)81-46-27-42-33(8-6-14-61(42)54(67)80-31-36-25-48(73-2)50(75-4)29-44(36)63(70)71)23-40(46)55(39)38-10-9-34(21-37(38)52(65)82-55)51(64)57-11-15-76-17-19-78-20-18-77-16-12-58-59-56/h9-10,21-29H,5-8,11-20,30-31H2,1-4H3,(H,57,64) |
| InChI key | IWBUKVVLULQKCE-UHFFFAOYSA-N |
| Storage Temp. | -20 °C |
Application
Photoactivatable rhodamine derivative functionalized with a PEG azide. The azide functionality can be used to conjugate this caged rhodamine to alkyne or cycloalkyne containing compounds or biomolecules using the azide-alkyne cycloaddition click chemistry reaction. The ortho-Nitroveratryloxycarbonyl (NVOC) cages can be removed upon irradiation with UV light, restoring the fluorescence of the base dye. NVOC has an absorption max at ~350 nm and has been shown to be cleaved at 350 nm, 405 nm and 420 nm.Q-Rhodamine λ(ex) = 537 nm, λ(em) = 556 nm.
Safety Information
| Storage Class Code | 11 - Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
