Cat#: CCR-0239
N6-Propargyl-ATP sodium salt
Synonyms (s): (N6pATP) sodium salt, N6-Propargyl-adenosine-5’-triphosphate sodium salt
Empirical Formula (Hill Notation): C13H18N5O13P3 · xNa+
Size: 1 mg
Product Introduction
| Molecular Weight | 545.23 (free acid basis) |
| NACRES | NA.22 |
| PubChem Substance ID | 329769102 |
| Assay | ≥95% (HPLC) |
| Form | Solid |
| Reaction Suitability | Reaction type: click chemistry |
| Smiles String | O[C@@H]([C@H]1O)[C@@H](COP(O)(OP(O)(OP(O)(O)=O)=O)=O)O[C@@H]1N2C=NC3=C2N=CN=C3NCC#C |
| InChI | 1S/C13H18N5O13P3/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(20)9(19)7(29-13)4-28-33(24,25)31-34(26,27)30-32(21,22)23/h1,5-7,9-10,13,19-20H,3-4H2,(H,24,25)(H,26,27)(H,14,15,16)(H2,21,22,23)/t7-,9-,10-,13?/m1/s1 |
| InChI key | MUOIWXPACQCYQC-RJNFYWFKSA-N |
| Storage Temp. | -20 °C |
Application
N6-Propargyl-ATP is suitable for in vitro AMPylation of proteins as well as in vitro polyadenylation of RNA. The resulting alkyne-functionalized protein or RNA can be processed using Cu(I)-catalyzed click chemistry to attach azide-labeled molecules. This gives options such as introduction of a biotin group for purification tasks, introduction of a fluorescent group for detection, or crosslinking to other azide-functionalized biomolecules.
Safety Information
| Storage Class Code | 13 - Non Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
