Cat#: CCR-0026
N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Synonyms (s): (1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate, BCN-amine
Empirical Formula (Hill Notation): C17H28N2O4
Size: 25 mg; 100 mg
Product Introduction
Molecular Weight | 324.42 |
NACRES | NA.22 |
CAS Number | 1263166-93-3 |
MDL Number | MFCD19705418 |
PubChem Substance ID | 329765726 |
Form | Liquid |
Reaction Suitability | Reaction type: click chemistry |
Smiles String | [H][C@@]12CCC#CCC[C@]1([H])[C@@H]2COC(NCCOCCOCCN)=O |
InChI | 1S/C17H28N2O4/c18-7-9-21-11-12-22-10-8-19-17(20)23-13-16-14-5-3-1-2-4-6-15(14)16/h14-16H,3-13,18H2,(H,19,20)/t14-,15+,16- |
InChI key | YZGOWXGENSKDSE-MUJYYYPQSA-N |
Storage Temp. | -20 °C |
Application
Amine functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide functionalized compounds or biomolecules without the need for a copper catalyst to result in a stable triazole linkage.
N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane may be used to functionalize hyaluronic acid with bicyclo[6.1.0]nonyne (BCN) for the development of responsive HA-based physical hydrogels with tunable properties.
Safety Information
Storage Class Code | 12 - Non Combustible Liquids |
WGK | WGK 3 |
For research use only. Not for clinical use.