Cat#: CCR-0016
L-Azidohomoalanine hydrochloride
Synonyms (s): AHA
Empirical Formula (Hill Notation): C4H8N4O2 · HCl
Size: 100 mg
Product Introduction
| Molecular Weight | 180.59 |
| CAS Number | 942518-29-8 |
| Form | Powder or Crystals |
| Reaction Suitability | Reaction type: click chemistry |
| Storage Temp. | -20 °C |
Application
L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click ” reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.
Safety Information
| Signal Word | Danger |
| Hazard Classifications | H242 |
| Storage Class Code | 5.2 - Organic peroxides and self-reacting hazardous materials |
| WGK | WGK 3 |
For research use only. Not for clinical use.
