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Dibenzocyclooctyne-PEG4-acid

Cat#: CCR-0060

Dibenzocyclooctyne-PEG4-acid

Synonyms (s): DBCO-PEG4-Acid

Empirical Formula (Hill Notation): C32H40N2O8

Size: 5 mg; 50 mg

Product Introduction

Molecular Weight 580.67
NACRES NA.22
MDL Number MFCD22380749
PubChem Substance ID 329766822
Form Solid
Reaction Suitability Reaction type: click chemistry
Smiles String O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
InChI 1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)
InChI key RMYANOWYMFCGGS-UHFFFAOYSA-N
Storage Temp. -20 °C

Application

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.
Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions.

Safety Information

Storage Class Code 13 - Non Combustible Solids
WGK WGK 3

For research use only. Not for clinical use.