Cat#: CLP-0040
Dibenzocyclooctyne-maleimide
Synonyms (s): DBCO-maleimide
Empirical Formula (Hill Notation): C25H21N3O4
Size: 1 mg; 5 mg; 50 mg
Product Introduction
| Molecular Weight | 427.45 |
| NACRES | NA.22 |
| MDL Number | MFCD22380750 |
| PubChem Substance ID | 329766887 |
| Form | Solid |
| Reaction Suitability | Reaction type: Click chemistry; Reagent type: Cross-linking reagent |
| Smiles String | O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O |
| InChI | 1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29) |
| InChI key | NHFQNAGPXIVKND-UHFFFAOYSA-N |
| Storage Temp. | -20 °C |
Application
Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Applications Include: Protein-peptide conjugatesAntibody-enzyme or antibody-drug conjugatesProtein or peptide-oligonucleotide conjugates Surface modification
Safety Information
| Signal Word | Warning |
| Hazard Classifications | Aquatic Acute 1 |
| Storage Class Code | 13 - Non Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
