Cat#: CLP-0067
CBTF
Synonyms (s): APN-TFS ester, Sodium 4-((4-(cyanoethynyl)benzoyl)oxy)-2,3,5,6-tetrafluorobenzenesulfonate
Empirical Formula (Hill Notation): C16H4F4NNaO5S
Size: 50 mg
Product Introduction
| Molecular Weight | 421.26 |
| NACRES | NA.22 |
| PubChem Substance ID | 329768745 |
| Form | Powder |
| Reaction Suitability | Reagent type: Cross-linking reagent |
| Smiles String | O=C(OC1=C(F)C(F)=C(S(=O)(O[Na])=O)C(F)=C1F)C2=CC=C(C#CC#N)C=C2 |
| InChI | 1S/C16H5F4NO5S.Na/c17-10-12(19)15(27(23,24)25)13(20)11(18)14(10)26-16(22)9-5-3-8(4-6-9)2-1-7-21;/h3-6H,(H,23,24,25);/q;+1/p-1 |
| InChI key | YFJYSJRZDOWXDH-UHFFFAOYSA-M |
| Storage Temp. | -20 °C |
Application
CBTF is a bifunctional crosslinker for amine-to-thiol coupling. The coupling can be performed with high selectivity in biological medium using mild reaction conditions. CBTF readily reacts with organic amines in basic conditions to produce APN-probes suitable for cysteine labeling.
Safety Information
| Signal Word | Danger |
| Hazard Classifications | Acute Tox. 3 Oral |
| Storage Class Code | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
For research use only. Not for clinical use.
