Cat#: CCR-0269
5-Norbornene-2-endo-acetic acid
Synonyms (s): Bicyclo[2.2.1]hept-5-en-2-ylacetic acid, Norbornene acetic acid
Empirical Formula (Hill Notation): C9H12O2
Size: 250 mg; 1 g
Product Introduction
| Molecular Weight | 152.19 |
| CAS Number | 825-71-8 |
| PubChem Substance ID | 329766608 |
| Form | Liquid |
| Reaction Suitability | Reaction type: click chemistry |
| Smiles String | OC(CC1C[C@@H]2C=C[C@H]1C2)=O |
| InChI | 1S/C9H12O2/c10-9(11)5-8-4-6-1-2-7(8)3-6/h1-2,6-8H,3-5H2,(H,10,11)/t6-,7+,8?/m1/s1 |
| InChI key | HRVGJQMCNYJEHM-KVARREAHSA-N |
Application
Carboxylic acid functionalized norbornene. Carboxylic acid can be used to modify amine containing compounds such as lysine residues on proteins/peptides via standard peptide coupling methods. Norbornene has been shown to react with 1,2,4,5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction, which is a bioorthogonal click chemistry reaction demonstrated to be useful in biological imaging applications.
Safety Information
| Signal Word | Warning |
| Hazard Classifications | H302 - H412 |
| Storage Class Code | 10 - Combustible liquids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
