Cat#: CCR-0093
5-Norbornene-2-acetic acid succinimidyl ester
Synonyms (s): 2,5-Dioxopyrrolidin-1-yl 2-(bicyclo[2.2.1]hept-5-en-2-yl)acetate, 5-Norbornene-2-acetic acid NHS, Bicyclo[2.2.1]hept-5-ene-2-acetic acid N-hydroxysuccinimide ester, Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester
Empirical Formula (Hill Notation): C13H15NO4
Size: 25 mg; 100 mg
Product Introduction
| Molecular Weight | 249.26 |
| NACRES | NA.22 |
| CAS Number | 1234203-45-2 |
| PubChem Substance ID | 329767816 |
| Assay | 97% |
| Form | Solid |
| Reaction Suitability | Reaction type: click chemistry |
| Smiles String | O=C(N1OC(C[C@H]2[C@@H]3C=C[C@@H](C3)C2)=O)CCC1=O |
| InChI | 1S/C13H15NO4/c15-11-3-4-12(16)14(11)18-13(17)7-10-6-8-1-2-9(10)5-8/h1-2,8-10H,3-7H2 |
| InChI key | AOGNOQQTUYLDKN-UHFFFAOYSA-N |
| Storage Temp. | 2-8 °C |
Application
Succinimidyl ester functionalized norbornene. Succinimidyl ester group will react with amine containing compounds such as lysine residues on proteins/peptides. Norbornene has been shown to react with 1; 2; 4; 5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction which is a bioorthogonal reaction demonstrated to be useful in biological imaging applications.
Safety Information
| Signal Word | Warning |
| Hazard Classifications | H302 |
| Storage Class Code | 11 - Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
