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4-(4′-Hydroxyphenylazo)benzoic acid

Cat#: CLP-0158

4-(4′-Hydroxyphenylazo)benzoic acid

Synonyms (s): (E)-4-[(4-Hydroxyphenyl)azo]benzoic acid

Empirical Formula (Hill Notation): C13H10N2O3

Size: 50 mg; 250 mg

Product Introduction

Molecular Weight 242.23
NACRES NA.22
CAS Number 105299-45-4
MDL Number MFCD00225268
PubChem Substance ID 329767468
Form Solid
Reaction Suitability Reagent type: Cross-linking reagent; Reagent type: Linker
Smiles String OC(C1=CC=C(/N=N/C2=CC=C(O)C=C2)C=C1)=O
InChI 1S/C13H10N2O3/c16-12-7-5-11(6-8-12)15-14-10-3-1-9(2-4-10)13(17)18/h1-8,16H,(H,17,18)/b15-14+
InChI key HLVCZTOFOWHIJZ-CCEZHUSRSA-N
Storage Temp. 2-8 °C

Application

4-(4′-Hydroxyphenylazo)benzoic acid may be used to synthesize 4-(4-propyloxyphenylazo)benzoic acid via Williamson synthesis by reacting with 1-bromopropane.
Azobenzene cleavable linker. Treatment with sodium dithionite (sodium hydrosulfite) reduces azo functionality, cleaving the N-N bond to yield two primary amines.Has been used in proteomic and affinity chromatography applications.

Safety Information

Signal Word Warning
Hazard Classifications Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class Code 11 - Combustible Solids
WGK WGK 3

For research use only. Not for clinical use.