3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

Synonyms (s): Formyl sulfonyl fluoride alkyne, Probe building block

Empirical Formula (Hill Notation): C₁₂H₁₃FO₃SSi

Size: 100 mg

Product Introduction

Molecular Weight	284.38
NACRES	NA.22
CAS Number	2088829-13-2
Assay	≥95%
Form	Solid
Reaction Suitability	Reaction type: click chemistry
Smiles String	O=C([H])C1=CC(S(=O)(F)=O)=CC(C#C[Si](C)(C)C)=C1
Storage Temp.	-20 °C

Application

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl group, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Safety Information

Storage Class Code	13 - Non Combustible Solids
WGK	WGK 3

For research use only. Not for clinical use.