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3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

Cat#: CCR-0063

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

Synonyms (s): Carboxyl diazirine alkyne, Probe building block

Empirical Formula (Hill Notation): C8H10N2O2

Size: 50 mg

Product Introduction

Molecular Weight 166.18
CAS Number 1450754-37-6
MDL Number MFCD31433997
Form Liquid
Reaction Suitability Reaction type: click chemistry
Smiles String C#CCCC1(N=N1)CCC(O)=O
Storage Temp. -20 °C

Application

Used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Safety Information

Signal Word Danger
Hazard Classifications H242
Storage Class Code 5.2 - Organic peroxides and self-reacting hazardous materials
WGK WGK 3

For research use only. Not for clinical use.