Cat#: CCR-0215
2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid
Synonyms (s): Carboxyl diazirine alkyne, Probe building block
Empirical Formula (Hill Notation): C12H7F3N2O3
Size: 25 mg
Product Introduction
Molecular Weight | 284.19 |
CAS Number | 2187374-12-3 |
Assay | ≥95% |
Form | Powder |
Reaction Suitability | Reaction type: click chemistry |
Smiles String | C#CCOC1=CC(C2(N=N2)C(F)(F)F)=CC=C1C(O)=O |
Storage Temp. | -20 °C |
Application
2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Safety Information
Storage Class Code | 13 - Non Combustible Solids |
WGK | WGK 3 |
For research use only. Not for clinical use.