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Cat#: CCR-0073
2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester
Synonyms (s): 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
Empirical Formula (Hill Notation): C27H16F5O4P
Size: 25 mg; 100 mg
Product Introduction
| Molecular Weight | 530.38 |
| NACRES | NA.22 |
| MDL Number | MFCD09265125 |
| PubChem Substance ID | 24885463 |
| Assay | 97% |
| Form | Solid |
| Reaction Suitability | Reaction type: click chemistry |
| Smiles String | COC(=O)c1ccc(cc1P(c2ccccc2)c3ccccc3)C(=O)Oc4c(F)c(F)c(F)c(F)c4F |
| InChI | 1S/C27H16F5O4P/c1-35-27(34)18-13-12-15(26(33)36-25-23(31)21(29)20(28)22(30)24(25)32)14-19(18)37(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-14H,1H3 |
| InChI key | OURNVXDJALDDIG-UHFFFAOYSA-N |
| Storage Temp. | -20 °C |
Application
Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules.The amine functionalized molecule first reacts with the phosphine through the activated pentafluorophenyl ester.The azide-molecule is then reacted with the newly labeled phosphine to form the iminophosphorane, and the aza-ylide is subsequently captured by the methyl ester to yield the covalent conjugated product.The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method
Safety Information
| Storage Class Code | 13 - Non Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
