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Dehydrocostus Lactone
SPC-00677
CAS No. 477-43-0
| Size | Price |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
IκB/IKK inhibitor
| Description |
|---|
| Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 477-43-0 |
| Description | Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties. |
| Formula | C15H18O2 |
| Molecular Weight | 230.30 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | N/A |
| SMILES | C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.