Online Inquiry
DDR1 Antibody
SPA-02858
| Size | Price |
| 100 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | DDR1 |
| Gene Abbr. | DDR1 |
| Gene ID | 780 |
| Full Name | discoidin domain receptor tyrosine kinase 1 |
| Alias | CAK, CD167, DDR, EDDR1, HGK2 |
| Introduction | The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2. They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling. Research studies have implicated aberrant expression and signaling of DDRs in human diseases related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis, and tumor invasion. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 3E3 |
| Isotype | IgG Kappa |
| Immunogen | Recombinant human DDR1 extracellular domain. |
| Usage | |
|---|---|
| Application | WB, ELISA |
| MW(KDa) | 125 |
| Reactivity | Human |
| Specificity | This antibody binds specifically to the extracellular domain of human DDR1. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.02% Proclin 300 |
| Storage Temp. | Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.