DC-SIGNR/CD299/CLEC4M Antibody - CD BioSciences

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DC-SIGNR/CD299/CLEC4M Antibody

DC-SIGNR/CD299/CLEC4M Antibody

SPA-02837

Size Price
25 µg Online Inquiry
500 µg Online Inquiry
More Options Online Inquiry
Target Information
Target Name DC-SIGNR/CD299
Gene Abbr. CLEC4M
Gene ID 10332
Full Name C-type lectin domain family 4 member M
Alias CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR
Introduction This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 120604
Isotype IgG2B
Immunogen NIH-3T3 mouse embryonic fibroblast cell line transfected with human DC‑SIGNR/CD299. Accession # Q9H2X3.
Usage
Application FC
Dilutions Flow Cytometry (2.5 µg/10^6 cells)
Reactivity Human
Specificity Detects human DC‑SIGNR/CD299.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.