DC-SIGNR/CD299/CLEC4M Antibody - CD BioSciences

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DC-SIGNR/CD299/CLEC4M Antibody

DC-SIGNR/CD299/CLEC4M Antibody

SPA-02833

Size Price
0.1 mg Online Inquiry
More Options Online Inquiry
Target Information
Target Name DC-SIGNR/CD299
Gene Abbr. CLEC4M
Gene ID 10332
Full Name C-type lectin domain family 4 member M
Alias CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR
Introduction This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 2G1
Isotype IgG3 Lambda
Immunogen CLEC4M (NP_055072, 285 a.a. ~ 394 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAA.
Usage
Application WB, ELISA
Dilutions Western Blot (1:500)
Reactivity Human
Specificity CLEC4M - C-type lectin domain family 4, member M.
Storage & Handling
Storage Buffer In 1X PBS, pH 7.4.
Preservative No Preservative
Storage Temp. Aliquot and store at -20 °C or -80 °C.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.