DC-SIGNR/CD299/CLEC4M Antibody - CD BioSciences

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DC-SIGNR/CD299/CLEC4M Antibody

DC-SIGNR/CD299/CLEC4M Antibody

SPA-02830

Size Price
0.1 mg Online Inquiry
More Options Online Inquiry
Target Information
Target Name DC-SIGNR/CD299
Gene Abbr. CLEC4M
Gene ID 10332
Full Name C-type lectin domain family 4 member M
Alias CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR
Introduction This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Recombinant Protein corresponding to amino acids: GLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGH.
Usage
Application IHC
Dilutions Immunohistochemistry (1:20-1:50)
Reactivity Human
Specificity Specificity of human DC-SIGNR/CD299/CLEC4M antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Storage & Handling
Storage Buffer PBS (pH 7.2) and 40% Glycerol.
Preservative 0.02% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.