Dasatinib - CD BioSciences

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Dasatinib

Dasatinib

SPC-00664

Dasatinib

CAS No. 302962-49-8

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Src inhibitor ; Bcr-Abl inhibitor ; c-Kit inhibitor ; Autophagy activator ; Apoptosis related activator

Description
Dasatinib (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
Product Details
CAS No. CAS No. 302962-49-8
Description Dasatinib (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
Formula C22H26ClN7O2S
Molecular Weight 488.01
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms BMS-354825
SMILES CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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