Dabrafenib Mesylate - CD BioSciences

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Dabrafenib Mesylate

Dabrafenib Mesylate

SPC-00646

Dabrafenib Mesylate

CAS No. 1195768-06-9

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Raf inhibitor

Description
Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.
Product Details
CAS No. CAS No. 1195768-06-9
Description Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.
Formula C23H20F3N5O2S2.CH4O3S
Molecular Weight 615.67
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms GSK2118436 Mesylate
SMILES CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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