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Dabrafenib Mesylate
SPC-00646
CAS No. 1195768-06-9
Size | Price |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
Raf inhibitor
Description |
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Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively. |
Product Details | |
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CAS No. | CAS No. 1195768-06-9 |
Description | Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively. |
Formula | C23H20F3N5O2S2.CH4O3S |
Molecular Weight | 615.67 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | GSK2118436 Mesylate |
SMILES | CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.