Cytochrome P450 1A1/1A2 Antibody - CD BioSciences

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Cytochrome P450 1A1/1A2 Antibody

Cytochrome P450 1A1/1A2 Antibody

SPA-02678

Size Price
100 µL Online Inquiry
0.025 mL Online Inquiry
More Options Online Inquiry
Target Information
Target Name Cytochrome P450
Gene Abbr. CYP1A1
Gene ID 1543
Full Name cytochrome P450 family 1 subfamily A member 1
Alias AHH, AHRR, CP11, CYP1, CYPIA1
Introduction In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. MC1
Isotype IgG1
Immunogen 3-methylcholanthrene induced rat cytochrome P450 protein.
Usage
Application WB, IF, IHC
Dilutions Western Blot (1:500); Immunofluorescence (1:20-1:200); Immunohistochemistry (1:50-1:200)
Reactivity Human, Mouse, Rat, Primate
Specificity Detects Cytochrome P450 1A1 (Gene ID: 1543, UniProt P04798) and Cytochrom P450 1A2 (Gene ID: 1544, UniProt: P05177) from human samples.
Storage & Handling
Storage Buffer Ascites.
Preservative 0.05% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Avoid freeze-thaw cycles.

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