Cytochrome c Antibody - CD BioSciences

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Cytochrome c Antibody

Cytochrome c Antibody

SPA-02674

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Target Information
Target Name Cytochrome c
Gene Abbr. CYCS
Gene ID 54205
Full Name cytochrome c, somatic
Alias CYC, HCS, THC4
Introduction Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form. This event further triggers caspase-3 activation and eventually leads to apoptosis.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 2.7D5
Isotype IgG2A
Immunogen Pigeon Cytochrome c.
Usage
Application IP
Dilutions Immunoprecipitation (1 μg/10^6 cells)
MW(KDa) 14
Reactivity Human, Mouse, Rat
Specificity Detects native human, mouse, and rat Cytochrome c.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.