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Cytochrome c Antibody
SPA-02673
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Cytochrome c |
| Gene Abbr. | CYCS |
| Gene ID | 54205 |
| Full Name | cytochrome c, somatic |
| Alias | CYC, HCS, THC4 |
| Introduction | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form. This event further triggers caspase-3 activation and eventually leads to apoptosis. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | CYCS/1010 |
| Isotype | IgG2B Kappa |
| Immunogen | Recombinant full-length human CYCS protein. |
| Usage | |
|---|---|
| Application | WB, FC, IHC, IF |
| Dilutions | Western Blot (0.5-1.0 µg/mL); Flow Cytometry (0.5-1 µg/10^6 cells in 0.1 mL); Immunofluorescence (0.5-1.0 µg/mL) |
| MW(KDa) | 14 |
| Reactivity | Human, Rat |
| Specificity | It recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached). |
| Storage & Handling | |
|---|---|
| Storage Buffer | 10 mM PBS with 0.05% BSA. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.