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Cytochrome c Antibody
SPA-02671
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Cytochrome c |
| Gene Abbr. | CYCS |
| Gene ID | 54205 |
| Full Name | cytochrome c, somatic |
| Alias | CYC, HCS, THC4 |
| Introduction | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form. This event further triggers caspase-3 activation and eventually leads to apoptosis. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 2B5F8 |
| Isotype | IgG2A |
| Immunogen | Equine Cytochrome c. |
| Usage | |
|---|---|
| Application | IHC, IP, IF |
| Dilutions | Immunohistochemistry (8-25 µg/mL); Immunoprecipitation (1 µg/10^6 cells); Immunofluorescence (8-25 µg/mL) |
| MW(KDa) | 14 |
| Reactivity | Human, Equine |
| Specificity | Detects native human Cytochrome c but not mouse Cytochrome c. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.