CYP19A1 (-) Cell Line - CD BioSciences

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CYP19A1 (-) Cell Line

CYP19A1 (-) Cell Line

SPL-01087

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1 Unit Online Inquiry
Description
CYP19A1 (-)
Target Information
Target Name CYP19A1
Gene Abbr. CYP19A1
Gene ID 1588
Full Name cytochrome P450 family 19 subfamily A member 1
Alias ARO, ARO1, CPV1, CYAR, CYP19
Species Human
Introduction This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016].
Product Details
Cell Line Model HAP1
Genotype CYP19A1 (-)
Description CYP19A1 (-)
Parental Cell Line C631
Handling Specifications
Disclaimer This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.