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CXCR4 Antibody
SPA-02568
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CXCR4 |
| Gene Abbr. | CXCR4 |
| Gene ID | 7852 |
| Full Name | C-X-C motif chemokine receptor 4 |
| Alias | CD184, D2S201E, FB22, HM89, HSY3RR |
| Introduction | CXCR4 is a chemokine receptor that belongs to the G protein-coupled receptor family. It is activated by a small cytokine, CXCL12, also known as stromal cell derived factor 1 (SDF-1). The main function of CXCR4 is the mediation of the homing of progenitor cells in the bone marrow and their recruitment to sites of injury. More recently, CXCR4 has been studied, as a potential therapeutic target, in the context of autoimmune diseases as well as cancer, as the receptor is involved in the regulation of migration, proliferation, and survival of cancer cells. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic peptide (TEEMGSGDYDSMKEPCFREENANFNKC) corresponding to N-terminal extracellular domain of human CXCR4 receptor. |
| Usage | |
|---|---|
| Application | WB, ELISA, IHC |
| Dilutions | Western Blot (1:250); ELISA (1:25000); Immunohistochemistry (1:150) |
| MW(KDa) | 45-60 |
| Reactivity | Human, Rat |
| Specificity | Peptide sequence is < 50% identical to other human chemokine receptors in this region. |
| Storage & Handling | |
|---|---|
| Storage Buffer | 10 mM KHPO4, 0.14 M NaCl and 1.0 mg/mL BSA. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.