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CXCR3 Antibody
SPA-02554
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CXCR3 |
| Gene Abbr. | CXCR3 |
| Gene ID | 2833 |
| Full Name | C-X-C motif chemokine receptor 3 |
| Alias | CD182, CD183, CKR-L2, CMKAR3, GPR9 |
| Introduction | This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 5C10E6 |
| Isotype | IgG1 |
| Immunogen | Purified recombinant fragment of human CD183 (AA: extra mix) expressed in E. coli. |
| Usage | |
|---|---|
| Application | WB, ELISA, FC, IHC |
| Dilutions | Western Blot (1:100-1:2000); ELISA (1:100-1:2000); Flow Cytometry (1:10-1:1000); Immunohistochemistry (1:10-1:1000) |
| Reactivity | Human |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.