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CXCR1/IL-8RA Antibody
SPA-02547
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CXCR1/IL-8RA |
| Gene Abbr. | CXCR1 |
| Gene ID | 3577 |
| Full Name | C-X-C motif chemokine receptor 1 |
| Alias | C-C, C-C-CKR-1, CD128, CD181, CDw128a |
| Introduction | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 42705 |
| Isotype | IgG2A |
| Immunogen | NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RA. Met1-Leu350. Accession # AAA59159. |
| Usage | |
|---|---|
| Application | FC, IHC |
| Dilutions | Flow Cytometry (0.25 µg/10^6 cells); Immunohistochemistry (8-25 µg/mL); Neutralization (0.4-2.0 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.