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Curcumin
SPC-00621
CAS No. 458-37-7
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 50 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Histone Acetyltransferase inhibitor; NF-κB inhibitor; HDAC inhibitor; Nrf2 activator; Anti-infection inhibitor; Autophagy activator; Apoptosis related activator; Ferroptosis inhibitor; Epigenetic Reader Domain inhibitor
| Description |
|---|
| Curcumin (Diferuloylmethane) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM） and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of transcription factor NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 458-37-7 |
| Description | Curcumin (Diferuloylmethane) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM） and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of transcription factor NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on. |
| Formula | C21H20O6 |
| Molecular Weight | 368.38 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Diferuloylmethane |
| SMILES | COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.