CUDC-101 - CD BioSciences

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CUDC-101

CUDC-101

SPC-00620

CUDC-101

CAS No. 1012054-59-9

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10 mM (1 mL in DMSO) Online Inquiry
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HDAC inhibitor ; EGFR inhibitor ; HER2 inhibitor

Description
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
Product Details
CAS No. CAS No. 1012054-59-9
Description CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
Formula C24H26N4O4
Molecular Weight 434.49
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.