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Chorionic Gonadotropin alpha Chain (hCG alpha) Antibody
SPA-04934
| Size | Price |
| 0.1 mL | Online Inquiry |
| 25 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | hCG |
| Gene Abbr. | CGA |
| Gene ID | 1081 |
| Full Name | glycoprotein hormones, alpha polypeptide |
| Alias | CG-ALPHA, FSHA, GPA1, GPHA1, GPHa |
| Introduction | Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. |
| Product Details | |
|---|---|
| Host | Sheep |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Native hCG. |
| Usage | |
|---|---|
| Application | ELISA |
| Dilutions | ELISA (1:500-1:1000) |
| Reactivity | Human |
| Specificity | This product is specific for human chorionic gonadotrophin (hCG), a 30kD hormone produced by placental syncytiotrophoblasts. hCG acts to maintain the corpus luteum until the developing placenta is able to produce the required levels of oestrogen and progesterone. hCG shares a common alpha chain with the pituitary hormones FSH, TSH and LH, but has a unique beta chain. This antibody reacts with intact hCG. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.09% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.