Chorionic Gonadotropin alpha Chain (hCG alpha) Antibody - CD BioSciences

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Chorionic Gonadotropin alpha Chain (hCG alpha) Antibody

Chorionic Gonadotropin alpha Chain (hCG alpha) Antibody

SPA-04915

Size Price
0.1 mL Online Inquiry
25 µL Online Inquiry
More Options Online Inquiry
Target Information
Target Name hCG
Gene Abbr. CGA
Gene ID 1081
Full Name glycoprotein hormones, alpha polypeptide
Alias CG-ALPHA, FSHA, GPA1, GPHA1, GPHa
Introduction Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 381012
Isotype IgG2A
Immunogen Mouse myeloma cell line NS0-derived recombinant human Chorionic Gonadotropin, alpha Chain ( alpha HCG) Ala25-Ser116. P01215.
Usage
Application WB, IHC
Dilutions Western Blot (1 µg/mL); Immunohistochemistry (8-25 µg/mL)
Reactivity Human
Specificity Detects human Chorionic Gonadotropin, alpha Chain ( alpha HCG) in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, no cross‑reactivity with recombinant human FSH beta or recombinant rat FSH beta is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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